How ancient masons harvested rock for Stonehenge19 February 2019 Read >
Faster, better, cheaper: the rise of CRISPR in disease detection19 February 2019 Read >
Why great white sharks dawdle their days away19 February 2019 Read >
Nearly half of US female scientists leave full-time science after first child19 February 2019 Read >
The giant Medusavirus turns defenceless cells to ‘stone’ 19 February 2019 Read >
Daily Briefing: What it’s like to be the ‘only one’19 February 2019 Read >
From the archive19 February 2019 Read >
Adventures of a bathynaut, art goes algorithmic, and CRISPR encapsulated: Books in brief19 February 2019 Read >
genetic; +178 new citations19 February 2019 Read >
Hydropower dams can help mitigate the global warming impact of wetlands19 February 2019 Read >
The society that turned Cambridge into a scientific powerhouse19 February 2019 Read >
Australia dials back effort to control ‘dual use’ research19 February 2019 Read >
genetic; +118 new citations19 February 2019 Read >
3D printing: don’t add to plastic pollution19 February 2019 Read >
Europe rules on harm from fluoroquinolone antibiotics19 February 2019 Read >
African swine fever could cause EU rift19 February 2019 Read >
A disadvantaged background doesn’t have to be a barrier to success19 February 2019 Read >
3D-printed lab parts can contaminate experiments19 February 2019 Read >
Groundwater-management plans — how well will they work?19 February 2019 Read >
To move research from quantity to quality, go beyond good intentions19 February 2019 Read >
Nutrition and its role in human evolution.18 February 2019 Read >
NAD+ metabolism as a target for metabolic health: have we found the silver bullet?18 February 2019 Read >
Neuroendocrine Neoplasms Associated with Germline Pathogenic Variants in the Homologous Recombination Pathway.18 February 2019 Read >
Feeding the world: improving photosynthetic efficiency for sustainable crop production.18 February 2019 Read >
Immunogenicity characterization of genetically fused or chemically conjugated heat-stable toxin (STa) toxoids of enterotoxigenic Escherichia coli (ETEC) in mice and pigs.18 February 2019 Read >
Sarcopenia and variation in the Human Leukocyte Antigen complex.18 February 2019 Read >
Effect of different solvent extracted samples from the leaves and fruits of Datura stramonium on the growth of bacteria and fungi.18 February 2019 Read >
Chromosome aberrations in bone marrow cells of rats treated with MTBE.18 February 2019 Read >
Effect of ionizing radiation on physiological and molecular processes in plants.18 February 2019 Read >
Rickets severity predicts clinical outcomes in children with X-linked hypophosphatemia: Utility of the radiographic Rickets Severity Score.18 February 2019 Read >
Unmasking the identity of toxigenic cyanobacteria driving a multi-toxin bloom by high-throughput sequencing of cyanotoxins genes and 16S rRNA metabarcoding.18 February 2019 Read >
Dissemination of Escherichia coli carrying plasmid-mediated quinolone resistance (PMQR) genes from swine farms to surroundings.18 February 2019 Read >
A tale of shells and claws: The signal crayfish as a threat to the pearl mussel Margaritifera margaritifera in Europe.18 February 2019 Read >
Patient-Reported Triggers of Paroxysmal Atrial Fibrillation.18 February 2019 Read >
Autoimmune and inflammatory K+-channelopathies in cardiac arrhythmias: clinical evidence and molecular mechanisms.18 February 2019 Read >
Curation and bioinformatic analysis of strabismus genes supports functional heterogeneity and proposes candidate genes with connections to RASopathies.18 February 2019 Read >
The study of interactions between genome and exposome in the development of systemic lupus erythematosus.18 February 2019 Read >
Lethal immunoglobulins: Autoantibodies and sudden cardiac death.18 February 2019 Read >
ATM mutation spectrum in Russian children with ataxia-telangiectasia.18 February 2019 Read >
Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates.18 February 2019 Read >
Review : Biotechnology of mycotoxins detoxification using microorganisms and enzymes.18 February 2019 Read >
HLA-B*14 allele predicts HIV-1 mother-to-child-transmission, in Salvador, Brazil.18 February 2019 Read >
Outcomes After Initial Unifocalization to a Shunt in Complex Tetralogy of Fallot with MAPCAs.18 February 2019 Read >
Evaluation of GDF15 as a therapeutic target of cardiometabolic diseases in human: A Mendelian randomization study.18 February 2019 Read >
SLC22A3 is associated with lipoprotein (a) concentration and cardiovascular disease in familial hypercholesterolemia.18 February 2019 Read >
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.18 February 2019 Read >
GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studies.18 February 2019 Read >
In utero intervention for severe congenital heart disease.18 February 2019 Read >
Prenatal diagnosis and management of congenital diaphragmatic hernia.18 February 2019 Read >
Analysis of the genetic architecture of energy balance and its major determinants dry matter intake and energy-corrected milk yield in primiparous Holstein cows.18 February 2019 Read >
Detection and molecular characterization of Giardia spp. in captive Psittaciformes in Brazil.18 February 2019 Read >
The Vitamins in Psychosis Study: A Randomized, Double-Blind, Placebo-Controlled Trial of the Effects of Vitamins B12, B6, and Folic Acid on Symptoms and Neurocognition in First-Episode Psychosis.18 February 2019 Read >
Genetic clues can be used to predict whether early-stage cancer will form an invasive tumour18 February 2019 Read >
Photonic topological insulator in synthetic dimensions18 February 2019 Read >
Daily Briefing: Both sides of the scalpel18 February 2019 Read >
Multiplex chromatin interactions with single-molecule precision18 February 2019 Read >
Announcing the 2019 ScientistAtWork photo competition18 February 2019 Read >
Huge variations in US postdoc salaries point to undervalued workforce18 February 2019 Read >
Baby’s mouth might hold sway over breast-milk microbiome18 February 2019 Read >
A young star is sprinkled with table salt18 February 2019 Read >
Integration of GWAS and brain eQTL identifies FLOT1 as a risk gene for major depressive disorder.17 February 2019 Read >
Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder.17 February 2019 Read >
Circulating CD14+CD163+CD209+ M2-like monocytes are associated with the severity of infection in Helicobacter pylori-positive patients.17 February 2019 Read >
Temporal and geographical variations in colorectal cancer incidence in Northern Iran 2004-2013.17 February 2019 Read >
Pumping the brakes: suppression of synapse development by MDGA-neuroligin interactions.17 February 2019 Read >
Photocatalytic degradation of local dyeing wastewater by iodine-phosphorus co-doped tungsten trioxide nanocomposites under natural sunlight irradiation.17 February 2019 Read >
Land subsidence hazard modeling: Machine learning to identify predictors and the role of human activities.17 February 2019 Read >
S. epidermidis strains from artisanal cheese made from unpasteurized milk in Poland - Genetic characterization of antimicrobial resistance and virulence determinants.17 February 2019 Read >
Clinical and genetic analysis of children with a dual diagnosis of Tourette syndrome and autism spectrum disorder.17 February 2019 Read >
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.17 February 2019 Read >
One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection.17 February 2019 Read >
Genetic risk of FCRL3 and FCRL5 polymorphisms in children with asthma and allergic rhinitis in a Chinese Han population.17 February 2019 Read >
Fin whale (Balaenoptera physalus) mitogenomics: A cautionary tale of defining sub-species from mitochondrial sequence monophyly.17 February 2019 Read >
Antiepileptic therapy approaches in KCNQ2 related epilepsy: A systematic review.17 February 2019 Read >
DNA and chromosomal damage in Senegalese sole (Solea senegalensis) as side effects of ozone-based water treatment - Contribution to optimization of fish-farming practices.17 February 2019 Read >
Whole exome sequencing revealed mutations in FBXL4, UNC80, and ADKin Thai patients with severe intellectual disabilities.17 February 2019 Read >
Fragile X mental retardation protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry.17 February 2019 Read >
UVB drives different stages of epigenome alterations during progression of skin cancer.17 February 2019 Read >
Caveolin-1 enhances metastasis formation in a human model of embryonal rhabdomyosarcoma through Erk signaling cooperation.17 February 2019 Read >
Interactions between plasmids and other mobile genetic elements affect their transmission and persistence.17 February 2019 Read >
Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging.17 February 2019 Read >
Validity of a rapid and simple fluorometric tripeptidyl peptidase 1 (TPP1) assay using dried blood specimens to diagnose CLN2 disease.17 February 2019 Read >
Disruption of gene SPL35, encoding a novel CUE domain-containing protein, leads to cell death and enhanced disease response in rice.17 February 2019 Read >
Challenges of fertility preservation in non-oncological diseases.17 February 2019 Read >
Mortality after breast cancer as a function of time since diagnosis by estrogen receptor status and age at diagnosis.17 February 2019 Read >
Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers.17 February 2019 Read >
Yeast-Based Screens to Target Alpha-Synuclein Toxicity.17 February 2019 Read >
C. elegans as a Model for Synucleinopathies and Other Neurodegenerative Diseases: Tools and Techniques.17 February 2019 Read >
Studying α-Synuclein Conformation by Intact-Cell Cross-Linking.17 February 2019 Read >
Association and gene-gene interaction analyses for polymorphic variants in CTLA-4 and FOXP3 genes: role in susceptibility to autoimmune thyroid disease.17 February 2019 Read >
Genetic relationships among subspecies of Capparis spinosa L. from Tunisia by using ISSR markers.17 February 2019 Read >
Proteomic and genomic profiling of pancreatic cancer.17 February 2019 Read >
Genetic characterization of bovine coronavirus in Vietnam.17 February 2019 Read >
Just choice: a Danielsian analysis of the aims and scope of prenatal screening for fetal abnormalities.17 February 2019 Read >
Comparative transcriptomics analysis uncovers alternative splicing events and molecular markers in cabbage (Brassica oleracea L.).17 February 2019 Read >
Current Treatment Options for Breast Cancer Brain Metastases.17 February 2019 Read >
Unusual radiological and histological presentation of a diffuse leptomeningeal glioneuronal tumor (DLGNT) in a 13-year-old girl.17 February 2019 Read >
Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma.17 February 2019 Read >
Targeting angiogenesis in Duchenne muscular dystrophy.17 February 2019 Read >
Influence of Land Use and Cover on Toxicogenetic Potential of Surface Water from Central-West Brazilian Rivers.17 February 2019 Read >
Genome-Wide, Integrative Analysis Implicates Exosome-Derived MicroRNA Dysregulation in Schizophrenia.17 February 2019 Read >
Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes.17 February 2019 Read >
A Pregnancy Cohort to Study Multidimensional Correlates of Preterm Birth in India: Study Design, Implementation, and Baseline Characteristics of the Participants.17 February 2019 Read >
Genetics and epigenetics in primary Sjögren's syndrome.17 February 2019 Read >
Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase.17 February 2019 Read >
Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy.17 February 2019 Read >
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.17 February 2019 Read >
A novel variant of the human mitochondrial DnaJ protein, Tid1, associates with a human disease exhibiting developmental delay and polyneuropathy.17 February 2019 Read >
Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options.17 February 2019 Read >
A signal processing method for alignment-free metagenomic binning: multi-resolution genomic binary patterns.17 February 2019 Read >
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.17 February 2019 Read >
Reverse immunodynamics: a new method for identifying targets of protective immunity.17 February 2019 Read >
Single gametophyte sequencing reveals that crossover events differ between sexes in maize.17 February 2019 Read >
A mathematical-descriptor of tumor-mesoscopic-structure from computed-tomography images annotates prognostic- and molecular-phenotypes of epithelial ovarian cancer.17 February 2019 Read >
Multi-cohort study identifies social determinants of systemic inflammation over the life course.17 February 2019 Read >
MKK3 modulates JNK-dependent cell migration and invasion.17 February 2019 Read >
Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress.17 February 2019 Read >
Establishing a generalized polyepigenetic biomarker for tobacco smoking.17 February 2019 Read >
Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens.17 February 2019 Read >
Polygenic and sex specific architecture for two maturation traits in farmed Atlantic salmon.17 February 2019 Read >
Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15.17 February 2019 Read >
A commentary on population genetic testing for primary prevention: changing landscape and the need to change paradigm.17 February 2019 Read >
The genetic basis of Turner syndrome aortopathy.17 February 2019 Read >
Divergent mitochondrial lineages arose within a large, panmictic population of the Savannah sparrow (Passerculus sandwichensis).17 February 2019 Read >
Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation.17 February 2019 Read >
Gene-environment interactions related to blood pressure traits in two community-based Korean cohorts.17 February 2019 Read >
Exotic plant species are locally adapted but not to high UV-B radiation: a reciprocal multi-species experiment.17 February 2019 Read >
Profiling of rotavirus 3'UTR-binding proteins reveals the ATP synthase subunit ATP5B as a host factor that supports late-stage virus replication.17 February 2019 Read >
A Family of NAI2-Interacting Proteins in the Biogenesis of the ER Body and Related Structures.17 February 2019 Read >
TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival.17 February 2019 Read >
The underacknowledged PPA-ALS: A unique clinicopathologic subtype with strong heritability.17 February 2019 Read >
Vitamin D levels and risk of delirium: A mendelian randomization study in the UK Biobank.17 February 2019 Read >
Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes.17 February 2019 Read >
Chromosome-Wide Evolution and Sex Determination in the Three-Sexed Nematode Auanema rhodensis.17 February 2019 Read >
Disruption of quorum sensing and virulence in Burkholderia cenocepacia by a structural analogue of the cis-2-dodecenoic acid signal.17 February 2019 Read >
Multilocus sequence analysis reveals three distinct populations of 'Candidatus Phytoplasma palmicola' with a specific geographical distribution on the African continent.17 February 2019 Read >
Characterization and treatment of congenital thrombotic thrombocytopenic purpura.17 February 2019 Read >
Genetic interactions support an inhibitory relationship between bone morphogenetic protein 2 and netrin 1 during semicircular canal formation.17 February 2019 Read >
Non-apoptotic function of Drosophila caspase activation in epithelial thorax closure and wound healing.17 February 2019 Read >
VERNALIZATION1 controls developmental responses of winter wheat under high ambient temperatures.17 February 2019 Read >
Is there etiologic heterogeneity between subtypes of childhood acute lymphoblastic leukemia? A review of variation in risk by subtype.17 February 2019 Read >
Reevaluating the pathogenicity of the mutation c.1194 +5 G>A in GAA gene by functional analysis of RNA in a 61-year-old woman diagnosed with Pompe disease by muscle biopsy.17 February 2019 Read >
Arrest of Fetal Brain Development in ALG11-Congenital Disorder of Glycosylation.17 February 2019 Read >
Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis.17 February 2019 Read >
Backtracking search optimization heuristics for nonlinear Hammerstein controlled auto regressive auto regressive systems.17 February 2019 Read >
Control of invasive sea lampreys using the piscicides TFM and niclosamide: Toxicology, successes & future prospects.17 February 2019 Read >
Self-reported functional health status following interrupted aortic arch repair: A Congenital Heart Surgeons' Society Study.17 February 2019 Read >
Genetic deletion of β2 adrenergic receptors exacerbates hepatocellular lipid accumulation in high-fat diet mice.17 February 2019 Read >
Immunogenicity and protective potential of Bordetella pertussis biofilm and its associated antigens in a murine model.17 February 2019 Read >
Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification.17 February 2019 Read >
A Novel Rare Missense Variation of the NOD2 Gene: Evidencesof Implication in Crohn's Disease.17 February 2019 Read >
The Value of Histological Algorithms to Predict the Malignancy Potential of Pheochromocytomas and Abdominal Paragangliomas-A Meta-Analysis and Systematic Review of the Literature.17 February 2019 Read >
Haplotype and Haplotype-Environment Interaction Analysis Revealed Roles of SPRY2 for NSCL/P among Chinese Populations.17 February 2019 Read >
Population Genetic and Functional Analysis of a cis-Regulatory Polymorphism in the Drosophila melanogaster Metallothionein A gene.17 February 2019 Read >
From Human Cytogenetics to Human Chromosomics.17 February 2019 Read >
Overexpression of StDREB2 Transcription Factor Enhances Drought Stress Tolerance in Cotton (Gossypium barbadense L.).17 February 2019 Read >
The Phylogeographic Diversity of EBV and Admixed Ancestry in the Americas⁻Another Model of Disrupted Human-Pathogen Co-Evolution.17 February 2019 Read >
The Roles of prM-E Proteins in Historical and Epidemic Zika Virus-mediated Infection and Neurocytotoxicity.17 February 2019 Read >
New Insights on Arabidopsis thaliana Root Adaption to Ammonium Nutrition by the Use of a Quantitative Proteomic Approach.17 February 2019 Read >
Targeting the Tetraspanins with Monoclonal Antibodies in Oncology: Focus on Tspan8/Co-029.17 February 2019 Read >
Trump science adviser calls for more collaboration between industry and government16 February 2019 Read >
genetic; +261 new citations16 February 2019 Read >
genetic; +261 new citations16 February 2019 Read >
Hungary’s scientists outraged by government budget grab15 February 2019 Read >
Daily briefing: How one academic couple solved the two-body problem15 February 2019 Read >
Antarctic voyage will explore ocean hidden under ice for 100,000 years15 February 2019 Read >
Rare trial of open peer review allays common concerns15 February 2019 Read >
Indian payment-for-papers proposal rattles scientists15 February 2019 Read >
genetic; +258 new citations15 February 2019 Read >
genetic; +258 new citations15 February 2019 Read >
The vaporized rock and extreme heat at a huge landslide’s heart15 February 2019 Read >
