The ‘Alzheimer’s Disease DNA Test’ from Genebase analyses your DNA. It reports on the presence of a genetic variant associated to the development of late-onset Alzheimer’s disease.
You’ll receive a report on the two variants of the APOE gene that you possess, and how this affects your risk of developing late-onset Alzheimer’s disease. The possible outcomes are:
e4/e4 – Two copies of the e4 variant are associated to a 10-15 fold increase in the risk
e3/e4 or e2/e4 – A single copy of the e4 variant increases the risk three-fold
e3/e3 – Two copies of the e3 variant do not affect the risk
e2/e2 or e2/e3 – One or two copies of the e2 variant is protective and reduces the risk